PIDE Project

Access to the Particle Irradiation Data Ensemble

PIDE is:

  • A radiobiological data base compiling more than 800 pairs of in-vitro cell survival experiments after photon and ion irradiation
  • A compilation of results drawn from about 75 publications
  • Convenient to study the relative biological effectiveness (RBE) for clonogenic cell survival as endpoint, or to benchmark RBE predicting models against experimental data
  • Using the linear quadratic model to parameterize the radiosensitivity of the cell lines
  • Discriminating between biological target, radiation quality and delivery techniques; all of these are relevant for RBE
  • Presented as tables stored in an Excel file
  • Freely available to the research community after registration on this home page
  • Updated on a regular basis (about once a year)
  • Being developed continuously by gathering new publications, so hints from the community about publications missing so far in PIDE are most welcome
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Publication:

Details on the development of PIDE as well as first results are published in [1]. It is the reference publication for PIDE.

News

04.01.2013

Launch of PIDE Project site

06.03.2013

A contribution of the PIDE project was published on the NASA website The Health Risks of Extratesetrial Environments (THREE). THREE is intended as an educational compendium as well as an information source and teaching tool for both researchers and students.

Download:

Please register here and you will be provided with the files via e-mail as soon as possible.

If you download the PIDE, you will find the following files:

  • Information_sheet.pdf<//span>: In this file some remarks on the usage of PIDE data are given.
    PLEASE READ CAREFULLY to avoid inconvenience!
  • pide_x.x.xls:  Data base with version number x.x
  • References.pdf<//span>:  List of references used in PIDE
  • Overview_table.pdf<//span>: A table giving an overview of all publications entering PIDE in the way presented in [1].

All registered PIDE users will be informed via e-mail if updates are available or errors in the data base have been revealed. For this reason we kindly ask all users not to distribute the files among colleagues but rather ask them to register on this web site.

See here for an overview of the PIDE project.

Contact:

For questions, criticism, new contributions to PIDE or other inquiries, please contact us by mail:

Thomas Friedrich

Michael Scholz

References:

[1]

Friedrich T, Scholz U, Elsässer T, Durante M, Scholz M.

Systematic analysis of RBE and related quantities using a database of cell survival experiments with ion beam irradiation

J Radiat Res, 54 (3), pp.  494-514 (2013)

doi:10.1093/jrr/rrs114