Application of CMOS particle tracker

CMOS Mimosa-28 pixel sensors were used for several applications by measuring single charged particle trajectories with high spatial resolution. These sensors have been used as online beam monitoring for low-intensity experiments to verify the beam profiles. In addition, fluence perturbations due to fiducial markers used for image guidance in particle therapy were evaluated for proton and carbon ion beams [1] . The sensors were also used in a recent experiment for 4D online monitoring by measuring secondary charged particles and detecting high-density gradients in the case of lung cancer.

CMOS setup for particle therapy applications in GSI Cave M [figure from https://physicsworld.com/a/how-do-fiducial-markers-affect-particle-therapy-dose-distributions/]
CMOS measurement of the influence of fiducial markers, which are usually implanted in the body (visbility in X-Ray imaging) [figure from Reidel et al, doi: 10.3389/fonc.2022.830080]

References:
[1] Reidel et al, Experimental Comparison of Fiducial Markers Used in Proton Therapy: Study of Different Imaging Modalities and Proton Fluence Perturbations Measured With CMOS Pixel Sensors, Front. Oncol. (2022), doi: 10.3389/fonc.2022.830080


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