List of Publications

Publications 2024 to 2026

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Base-excision repair increases DNA double-strand break clustering within heavy-ion tracks and modulates repair at δ-electron-induced breaks
Scientific reports 16(1), 1339 () [10.1038/s41598-025-32823-z] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Differentiation and functionality of human bronchial epithelial cells in an air-liquid interface culture are modified by irradiation exposure
Frontiers in Public Health 13, 1706687 () [10.3389/fpubh.2025.1706687] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Synchrotron-based infrared microspectroscopy study on the biomolecular impact of carbon minibeam radiation therapy on a mouse osteosarcoma cell line
Infrared physics & technology 152, 106247 - () [10.1016/j.infrared.2025.106247] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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GSI-ESA-NASA Nuclear Cross-section Database: Update I. Addition of Proton-projectile Reaction Cross-sections
Health physics 130(2), 222 - 232 () [10.1097/HP.0000000000002055] BibTeX | EndNote: XML, Text | RIS

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Radiation-induced lymphopenia: A data compilation to unveil relevant factors and mitigation strategies
Clinical and translational radiation oncology 56, 101071 () [10.1016/j.ctro.2025.101071] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Relative biological effectiveness and neural stem cell fate in carbon ion–irradiated human brain organoids
Radiotherapy and oncology 214, 111224 () [10.1016/j.radonc.2025.111224] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Aberrant choroid plexus formation drives the development of treatment-related brain toxicity
Communications biology 8(1), 276 () [10.1038/s42003-025-07736-2] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Characterisation of the HollandPTC R&D proton beamline for physics and radiobiology studies
Physica medica 130, 104883 () [10.1016/j.ejmp.2024.104883] BibTeX | EndNote: XML, Text | RIS

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3934 Quality analysis and correction of ultra-precise 3D-printed patient specific range modulators in particle therapy
ESTRO 2025, ViennaVienna, Austria, 2 May 2025 - 6 May 20252025-05-022025-05-06 () [10.1016/S0167-8140(25)03022-1] BibTeX | EndNote: XML, Text | RIS

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Characterization of Fully Fragmented High-Energy Heavy-Ion Beams for SEE Testing Through Measurements and Simulations
IEEE transactions on nuclear science 72(4), 1123 - 1129 () [10.1109/TNS.2024.3492039] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Microdosimetry investigation of target fragments in proton therapy, assessing the impact of the detector type
Physics in medicine and biology 70(23), 235016 () [10.1088/1361-6560/ae1ee8] BibTeX | EndNote: XML, Text | RIS

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A response to the Vancouver call for action: addressing the needs of early career scientists in radiation protection
Radiation and environmental biophysics 64(4), 581 - 593 () [10.1007/s00411-025-01145-z] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Development and performance assessment of the BGO calorimeter module for the FOOT experiment
Journal of Instrumentation 20(03), P03021 - () [10.1088/1748-0221/20/03/P03021] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Including medium effects and longer temporal scales in TRAX-CHEMxt
Physics in medicine and biology 70(24), 245023 () [10.1088/1361-6560/ae29e1] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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An Evaluation of the Potential Radiosensitization Effect of Spherical Gold Nanoparticles to Induce Cellular Damage Using Different Radiation Qualities
Molecules 30(5), 1038 () [10.3390/molecules30051038] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The immunogenic potential of carbon ions and the involved mechanisms in tumor cells
Darmstadt : Technical University of Darmstadt 143 p. () [10.26083/TUPRINTS-00030033] = Dissertation, Technical University of Darmstadt, 2025   Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Development of human brain tumor assembloids that mimic the interaction of normal and tumorous tissue to assess the impact of ionizing radiation
Darmstadt : Technical University of Darmstadt 141 p. () [10.26083/TUPRINTS-00031050] = Dissertation, Technical University of Darmstadt, 2025   Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Integrative focus on the space exposome-integrome: physiological challenges and practical limits of countermeasures beyond low Earth orbit
npj microgravity 11(1), 82 () [10.1038/s41526-025-00537-1] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Gene Expression Profiling and Phenotypic Characterization of Circulating Tumor Cells Derived from a Murine Osteosarcoma Model
Cancers 17(7), 1210 () [10.3390/cancers17071210] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Radon exposure delays the development of skin lesions in a mouse model of psoriasis
Frontiers in immunology 16, 1638483 () [10.3389/fimmu.2025.1638483] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Experimental assessment of novel PET detector components for online imaging of radioactive ion beams
Physics in medicine and biology 70(19), 195008 () [10.1088/1361-6560/ae0674] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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A comparison of carbon ions versus protons for integrated mode ion imaging
Medical physics 52(5), 3097 - 3106 () [10.1002/mp.17645] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Radiation quality matters: morphological and biochemical responses of Brassica rapa microgreens to X-rays, C-ions, and Fe-ions
Planta 262(5), 118 () [10.1007/s00425-025-04835-6] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Real-time motion modeling and treatment verification for irregular motion in carbon ion therapy: a feasibility study
Physics in medicine and biology 70(16), 165009 () [10.1088/1361-6560/adf592] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Evaluation of motion mitigation strategies for carbon ion therapy of abdominal tumors based on non-periodic imaging data
Physics in medicine and biology 70(6), 065002 () [10.1088/1361-6560/adb89b] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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A generative adversarial network to improve integrated mode proton imaging resolution using paired proton–carbon data
Medical physics 52(9), e18081 () [10.1002/mp.18081] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Accelerator technologies for proton and ion beam therapy
Nature physics 21(9), 1363 - 1373 () [10.1038/s41567-025-02994-7] BibTeX | EndNote: XML, Text | RIS

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The HEARTS EU Project and Its Initial Results on Fragmented High-Energy Heavy-Ion Single-Event Effects Testing
IEEE transactions on nuclear science 72(4), 1040 - 1049 () [10.1109/TNS.2025.3530502] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Evaluation of proton and carbon ion beam models in TReatment Planning for Particles 4D (TRiP4D) referring to a commercial treatment planning system
Zeitschrift für medizinische Physik 35(2), 218 - 226 () [10.1016/j.zemedi.2023.06.002] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Sensing the Unsensed: Ionizing Radiation at the Boundaries of Human Perception
Physics of life reviews 55, 90-91 () [10.1016/j.plrev.2025.09.003] BibTeX | EndNote: XML, Text | RIS

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Human cerebral organoids model tumor initiation and infiltration in an autologous astrocyte-supported setting
iScience 28(9), 113334 () [10.1016/j.isci.2025.113334] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Variable Relative Biological Effectiveness of Protons in the Rat Spinal Cord: Measurements and Comparison With Model Calculations
Advances in radiation oncology 10(8), 101809 () [10.1016/j.adro.2025.101809] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Image-guided treatment of mouse tumours with radioactive ion beams
Nature physics 21(10), 1648 - 1656 () [10.1038/s41567-025-02993-8] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Comprehensive Robustness Evaluation of Proton and Carbon-Ion Plans in Thoracic Cancer Treatment
International journal of particle therapy 17, 101195 () [10.1016/j.ijpt.2025.101195] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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2-Deoxy-D-Glucose and ES-936 sensitize cancer- but not normal cells to both low- and high LET irradiation
Frontiers in oncology 15, 1633299 () [10.3389/fonc.2025.1633299] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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HyperSHArc: Single-Isocenter Stereotactic Radiosurgery of Multiple Brain Metastases Using Proton, Helium, and Carbon Ion Arc Therapy
Advances in radiation oncology 10(5), 101763 () [10.1016/j.adro.2025.101763] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Impact of Microdosimetric Modeling on Computation of Relative Biological Effectiveness for Carbon Ion Radiotherapy
Radiation 5(2), 21 () [10.3390/radiation5020021] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Angular differential and elemental fragmentation cross sections of a 400 MeV/nucleon $^{16}O$ beam on a graphite target with the FOOT experiment
Physical review / C 112(1), 014610 () [10.1103/nmw9-ldrm] BibTeX | EndNote: XML, Text | RIS

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Brains in space: impact of microgravity and cosmic radiation on the CNS during space exploration
Nature reviews / Neuroscience 26(6), 354 - 371 () [10.1038/s41583-025-00923-4] BibTeX | EndNote: XML, Text | RIS

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Induction of Cytoplasmic dsDNA and cGAS-STING Immune Signaling After Exposure of Breast Cancer Cells to X-ray or High-Energetic Carbon Ions
Advances in radiation oncology 10(6), 101783 () [10.1016/j.adro.2025.101783] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Dose Build-up of High-energy $^1$H and $^4$He Ions in Standard, Innovative and In Situ Shielding Materials for Space Radiation: Measurements and Simulations
Radiation research 203(3), 163-174 () [10.1667/RADE-24-00244.1] BibTeX | EndNote: XML, Text | RIS

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Carbon minibeam radiation therapy results in tumor growth delay in an osteosarcoma murine model
Scientific reports 15(1), 7305 () [10.1038/s41598-025-91872-6] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Feasibility study of 4D-online monitoring of density gradients induced by lung cancer treatment using carbon ions
Frontiers in oncology 15, 1502960 () [10.3389/fonc.2025.1502960] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Imaging lung tumor motion using integrated‐mode proton radiography—A phantom study towards tumor tracking in proton radiotherapy
Medical physics 52(2), 1146 - 1158 () [10.1002/mp.17508] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Radioresistant, Rare, Recurrent, and Radioinduced: 4Rs of Hadrontherapy for Patients Selections
International journal of particle therapy 15, 100737 - () [10.1016/j.ijpt.2024.100737] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Probing Spatiotemporal Effects of Intertrack Recombination with a New Implementation of Simultaneous Multiple Tracks in TRAX-CHEM
International journal of molecular sciences 26(2), 571 () [10.3390/ijms26020571] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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The FLUKA Monte Carlo simulation of the magnetic spectrometer of the FOOT experiment
Computer physics communications 307, 109398 () [10.1016/j.cpc.2024.109398] BibTeX | EndNote: XML, Text | RIS

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In vitro measurement of proton RBE: A multi-centric comparison using a harmonized setup
Clinical and translational radiation oncology 53, 100978 () [10.1016/j.ctro.2025.100978] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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FLASH Bragg-Peak Irradiation With a Therapeutic Carbon Ion Beam: First In Vivo Results
International journal of radiation oncology, biology, physics 121(5), 1282 - 1292 () [10.1016/j.ijrobp.2024.11.089] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Nuclear data for particle therapy
Strasbourg : Université de Strasbourg 180 p. () = Dissertation, Université de Strasbourg, 2024   Download fulltextFulltext BibTeX | EndNote: XML, Text | RIS

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Twenty-Five Years of Carbon Ion Radiotherapy in Europe
Nuclear physics news 34(4), 21 - 24 () [10.1080/10619127.2024.2410679] BibTeX | EndNote: XML, Text | RIS

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First dual isotope beam production for simultaneous heavy ion radiotherapy and radiography
15th International Particle Accelerator Conference, IPAC2024, NashvilleNashville, USA, 19 May 2024 - 24 May 20242024-05-192024-05-24 JACoW Publishing 1893-1896 pages1.5 MB () [10.18429/JACOW-IPAC2024-WEAN1] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Fast and accurate: probing the homogeneous biochemical stage of radiation damage with the new TRAX-CHEMxt code.
Heidelberg : Heidelberg University Library 123 p. () [10.11588/HEIDOK.00035575] = Dissertation, Heidelberg University, 2024   Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Understanding the scientific validity of synthetic torpor for radiation research and extended space missions
Frontiers in space technologies 5, 1471001 () [10.3389/frspt.2024.1471001] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Morphological and Photosynthetic Pigment Screening of Four Microgreens Species Exposed to Heavy Ions
Plants 13(24), 3541 - () [10.3390/plants13243541] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Radiation-induced DNA double-strand breaks in cortisol exposed fibroblasts as quantified with the novel foci-integrated damage complexity score (FIDCS)
Scientific reports 14(1), 10400 () [10.1038/s41598-024-60912-y] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Carbon ion mono-energetic and spread-out Bragg peak measurements using nanocomposite Fricke gel dosimeters with LET-independent response
Radiation measurements 176, 107175 () [10.1016/j.radmeas.2024.107175] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Multi-Target Inhibitor CUDC-101 Impairs DNA Damage Repair and Enhances Radiation Response in Triple-Negative Breast Cell Line
Pharmaceuticals 17(11), 1467 () [10.3390/ph17111467] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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BioMoon: a concept for a mission to advance space life sciences and astrobiology on the Moon
Earth, moon and planets 128(1), 5 () [10.1007/s11038-024-09558-4] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Inkorporation bei Radonexposition : Radonverteilung im Blut und Deposition der Zerfallsprodukte im Lungenmodell
Frankfurt am Main : Universitätsbibliothek Johann Christian Senckenberg 117 p. () = Dissertation, Goethe Universität Ffm, 2024   Download fulltextFulltext by OpenAccess repository BibTeX | EndNote: XML, Text | RIS

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Particle arc therapy: Status and potential
Radiotherapy and oncology 199, 110434 () [10.1016/j.radonc.2024.110434] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Exploring energy selection methods for robust biologically optimized carbon ion arc for head&neck cancer patients
Health and Technology 14(5), 873 - 888 () [10.1007/s12553-024-00877-0] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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A Fast 3D Range-Modulator Delivery Approach: Validation of the FLUKA Model on a Varian ProBeam System Including a Robustness Analysis
Cancers 16(20), 3498 () [10.3390/cancers16203498] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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On the Way to Accounting for Lung Modulation Effects in Particle Therapy of Lung Cancer Patients—A Review
Cancers 16(21), 3598 () [10.3390/cancers16213598] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Real-time delivered dose assessment in carbon ion therapy of moving targets
Physics in medicine and biology 69(20), 205001 () [10.1088/1361-6560/ad7d59] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Bonner sphere measurements of high-energy neutron spectra from a 1 GeV/u $^{56}Fe$ ion beam on an aluminum target and comparison to spectra obtained by Monte Carlo simulations
Frontiers in physics 12, 1456472 () [10.3389/fphy.2024.1456472] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Deep learning-based voxel sampling for particle therapy treatment planning
Physics in medicine and biology 69(15), 155014 () [10.1088/1361-6560/ad5bba] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Current status and future trends in particle therapy – lessons from an interdisciplinary workshop
workshop on cancer therapy using hadrons (proton, carbon ions or boron neutron capture therapy), PaviaPavia, Italy, 11 Oct 2023 - 12 Oct 20232023-10-112023-10-12 Health and Technology 14(5), 819 - 821 () [10.1007/s12553-024-00855-6] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Kaplan lecture 2023: lymphopenia in particle therapy
International journal of radiation biology 100(5), 669 - 677 () [10.1080/09553002.2024.2324472] BibTeX | EndNote: XML, Text | RIS

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Very-High-Energy Heavy Ion Beam Dosimetry Using Solid State Detectors for Electronics Testing
IEEE transactions on nuclear science 71(8), 1837 - 1845 () [10.1109/TNS.2024.3350667] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Carbon Ion and Photon Radiation Therapy Show Enhanced Antitumoral Therapeutic Efficacy With Neoantigen RNA-LPX Vaccines in Preclinical Colon Carcinoma Models
International journal of radiation oncology, biology, physics 119(3), 936 - 945 () [10.1016/j.ijrobp.2023.12.042] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Opportunities and challenges of upright patient positioning in radiotherapy
Physics in medicine and biology 69(18), 18TR02 () [10.1088/1361-6560/ad70ee] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Particle Beam Radiobiology Status and Challenges: A PTCOG Radiobiology Subcommittee Report
International journal of particle therapy 13, 100626 () [10.1016/j.ijpt.2024.100626] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model
Frontiers in oncology 14, 1427667 () [10.3389/fonc.2024.1427667] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Relative biological effectiveness of oxygen ion beams in the rat spinal cord: Dependence on linear energy transfer and dose and comparison with model predictions
Physics & Imaging in Radiation Oncology 30, 100581 () [10.1016/j.phro.2024.100581] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Mechanistic Sequence of Histone Deacetylase Inhibitors and Radiation Treatment: An Overview
Pharmaceuticals 17(5), 602 () [10.3390/ph17050602] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Investigation of the Impact of Temporal Dose Delivery Patterns of Ion Irradiation with the Local Effect Model
Radiation research 201(4), 275-286 () [10.1667/RADE-23-00074.1] BibTeX | EndNote: XML, Text | RIS

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Influenza Virus Inactivated by Heavy Ion Beam Irradiation Stimulates Antigen-Specific Immune Responses
Pharmaceutics 16(4), 465 () [10.3390/pharmaceutics16040465] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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[Editorial] System of radiological protection: Towards a consistent framework on Earth and in space
Zeitschrift für medizinische Physik 34(1), 4 - 13 () [10.1016/j.zemedi.2024.01.004] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Ground-based passive generation of Solar Particle Event spectra: Planning and manufacturing of a 3D-printed modulator
Zeitschrift für medizinische Physik 34(1), 153 - 165 () [10.1016/j.zemedi.2023.10.002] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Enhanced RBE of Particle Radiation Depends on Beam Size in the Micrometer Range
Radiation research 201(2), 140-149 () [10.1667/RADE-23-00217.1] BibTeX | EndNote: XML, Text | RIS

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Mechanistic model of radiotherapy-induced lung fibrosis using coupled 3D agent-based and Monte Carlo simulations
Communications medicine 4(16), 1-14 () [10.1038/s43856-024-00442-w] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Measurement of secondary neutron spectra induced by 480 MeV proton and 430 MeV/u 4 He beams with a thick aluminum target
16th Topical Seminar on Innovative Particle and Radiation Detectors, SienaSiena, Italy, 22 Sep 2023 - 29 Sep 20232023-09-222023-09-29 Journal of Instrumentation 19(01), C01035 () [10.1088/1748-0221/19/01/C01035] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Charge identification of fragments produced in 16O beam interactions at 200 MeV/n and 400 MeV/n on C and C2H4 targets
Frontiers in physics 11, 1327202 () [10.3389/fphy.2023.1327202] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
BMC biology 22(1), 11 () [10.1186/s12915-023-01807-8] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Osteo-immunological impact of radon spa treatment: due to radon or spa alone? Results from the prospective, thermal bath placebo-controlled RAD-ON02 trial
Frontiers in immunology 14, 1284609 () [10.3389/fimmu.2023.1284609] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Focus stacking single-event particle radiography for high spatial resolution images and 3D feature localization.
Physics in medicine and biology 69(2), 024001 () [10.1088/1361-6560/ad131a] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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Spectral composition of secondary electrons based on the Kiefer–Straaten ion track structure model
Physics in medicine and biology 69(2), 025013 () [10.1088/1361-6560/ad1765] OpenAccess  Download fulltext Files BibTeX | EndNote: XML, Text | RIS

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