dose radon exposure. To achieve this, we work together in the frame of the „GREWIS“-project with experts covering the fields of particle physics, cytogenetics and DNA repair, immunology, molecular cell [...] reactions, a “flow chamber” was constructed to mimic the shear stress caused by the blood flow. Experiments are performed in vitro using both primary mouse and human cells (hematopoietic, skin, bone, synovial [...] high doses of carbon ions, with a moderate release of inflammatory cytokines [24]. In ongoing experiments, the results are verified in carbon ion irradiated pig skin. © Dr. Julia Wiedemann, GSI Helmho