description of the setup for the pilot project Today, Cave M features a close-to-clinic delivery system without any clinical constraints, and moreover state-of-the-art option for small animal irradiation [...] The application of the scanned beam is controlled by a research version of CNAO ‘s dose delivery system, which we use to develop advanced motion mitigation and precision beam delivery strategies Cave M [...] Newhauser, M. Donetti, M. Durante, U. Weber, B. Zipfel, C. Hartmann-Sauter, M. Wolf and C. Graeff . A facility for the research, development, and translation of advanced technologies for ion-beam therapies